Rams vs Lions prediction and analysis

December 17, 2025
NFL Betting Predictions
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Game Overview

The Los Angeles Rams (10-3) host the Detroit Lions (8-5) at SoFi Stadium in what shapes up as a marquee NFC matchup. The market has Los Angeles as roughly a six-point favorite with an over/under in the mid-50s — a line that reflects two efficient offenses and a Rams defense that has proven stingy this season.

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Key Factors to Watch

  • Quarterback play: Matthew Stafford and Jared Goff are both playing at a high level, combining precision passing with experienced pocket presence. Stafford’s touchdown rate and Goff’s completion percentage make this a quarterback-driven game.
  • Passing corps: The Rams’ Puka Nacua–Davante Adams combo is one of the league’s best duos and creates matchup problems across the field. Detroit counters with Amon-Ra St. Brown and Jameson Williams, an explosive pair capable of breaking games open.
  • Running game balance: Jahmyr Gibbs powers the Lions’ ground attack while Kyren Williams gives the Rams a consistent complement. Both teams can use the run to control tempo and set up play-action, which is where both QBs thrive.
  • Defensive efficiency: Los Angeles ranks among the league leaders in points allowed; Detroit’s defense is respectable but not dominant. The Rams’ ability to limit explosive plays could be decisive in a tight game.
  • Situational trends: Home-field advantage at SoFi has favored the Rams, especially late in the season, while the Lions have shown resilience in road spots and as underdogs in recent years.

Matchup Analysis

Offensively, both teams live through their passing games but complement them with quality rushing attacks. The Rams feature two elite receivers who draw attention and free up intermediate options; Stafford’s tendency to target matchups vertically can generate quick chunk plays. Detroit’s offense is more balanced with Gibbs supplying home-run ability as a runner and the receiving corps converting underneath targets into yards after catch.

Defensively, Los Angeles has been more consistent in limiting scoring. If the Rams can contain the Lions’ explosive plays and force longer drives, they tilt the game to their favor. Conversely, Detroit’s front can disrupt rhythm if they win the line-of-scrimmage battle and make Stafford drive the field in longer possessions.

Special teams and turnover margin matter more in a heavyweight NFC tilt; both teams have playmakers who can swing field position. Expect coaching adjustments and situational aggressiveness down the stretch — both head coaches have playoff aspirations that should push them toward an assertive game plan.

Betting Angles and Totals

  • Spread: The Rams’ -6 on paper is justified by defensive metrics and home advantage, but Detroit’s recent history as an effective underdog and ability to cover moderate spreads deserves respect.
  • Over/Under: A mid-50s number reflects two efficient offenses. If both teams achieve early success through play-action and quick passes, this game can climb into the upper 50s. If the Rams slow the pace and convert drives into clock-killing possessions, the total could stay below the number.
  • Prop considerations: Look at reception and target props for Nacua and St. Brown. If the Lions are receiving points and forced to play catch-up, Jahmyr Gibbs receiving yards and Goff passing yard lines could climb.

Prediction Summary

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This is a classic clash between a disciplined, defense-anchored Rams unit and a versatile Lions team that can strike quickly through both run and pass. The Rams hold advantages in defensive efficiency and elite receiving matchups, but the Lions’ offensive balance and strong situational performance as underdogs keep this game within reach.

Given the spread and the way both offenses operate, I expect a competitive, high-leverage game that comes down to a handful of key plays. The Rams should be favored in regulation, but the number (+6 to the Lions) gives Detroit a realistic path to cover because of their ability to move the chains and force sustained drives. I’ll take the points with the visiting offense in a one-score projection.

Final Prediction: Detroit keeps it close and covers the number.

Prediction: Detroit Lions +6