Bengals vs Lions prediction and analysis

October 2, 2025
NFL Betting Predictions
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Game Overview

Sunday, Oct. 5 — Paycor Stadium, Cincinnati. Kickoff: 4:25 p.m. EDT. Line: Bengals +10.5, O/U 49.5.

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Current form and context

The Lions enter Week 5 at 3-1 after a convincing 34-10 win last week and have been clicking on offense all month. Jared Goff has been efficient (high completion percentage, multi-TD games) and Jahmyr Gibbs is carrying an explosive, well-balanced rushing attack. Detroit is averaging north of 34 points per game and looks like one of the league’s most productive offenses through four weeks.

Cincinnati (2-2) arrives off a brutal 28-3 loss to Denver that exposed multiple weaknesses: an anemic offense without Joe Burrow, poor third-down conversion rates, and a defense that was gashed both on the ground and through the air. Jake Browning has filled in but the passing attack is averaging just over 155 yards per game; the Bengals sit near the bottom of the league in total offense and rushing yards.

Key matchups to watch

  • Jared Goff vs. Bengals pass defense — Goff is operating with excellent timing and a top-tier slot target in Amon-Ra St. Brown. If the Bengals can’t pressure him, Detroit will sustain drives and pile up points.
  • Jahmyr Gibbs & Lions run game vs. Bengals front — The Bengals rank last in rushing yards allowed recently and have struggled to stop multi-dimensional backs. Gibbs’ ability to threaten both as a runner and receiver forces Cincinnati into difficult personnel decisions.
  • Ja’Marr Chase vs. Lions secondary — Chase remains Cincinnati’s clear No. 1 receiving threat, but with limited offensive balance around him and Browning’s conservative passing, Chase’s opportunities could be constrained.
  • Sacks and third-down pressure — Detroit generated multiple sacks last week; continuing to pressure Browning would shorten the game and keep Cincinnati off the field.

Situational factors and trends

Home-field advantage helps the Bengals, but situational trends favor Detroit: the Lions have been dominant after home wins and have covered large spreads on the road in recent seasons. Cincinnati’s offense without Burrow has been inconsistent; two straight games of being outscored heavily is a red flag. Special teams and turnovers will matter — Detroit has edged opponents in turnover margin recently, and a short field for Goff’s offense amplifies Cincinnati’s mistakes.

Projection and score expectation

Given the mismatch in offensive firepower and Cincinnati’s inability to move the ball consistently, I expect Detroit to control both tempo and the scoreboard. The Lions should be able to run effectively, chew clock, and convert red zone chances. Defensively, Detroit doesn’t have to shut the Bengals out — just limit explosive plays and force Browning into difficult down-and-distance situations.

Prediction Summary

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Final projection: Lions win by multiple scores. Expected range: Detroit 31, Cincinnati 14 — a 17-point margin. The Lions’ offense should be able to exploit a Bengals defense that has been vulnerable, while Cincinnati’s offense is unlikely to produce enough sustained drives to keep this game close.

Betting angle

Main play: Take Detroit -10.5. This spread is large but justified by the mismatch at quarterback, the Lions’ sustained offensive efficiency, and the Bengals’ recent offensive struggles without Burrow. If you want a secondary play, consider the Lions to cover and the game to finish UNDER 49.5 — Detroit’s ability to dominate possession combined with Cincinnati’s low scoring upside makes a clock-control script plausible.

Final prediction

Prediction: Detroit Lions -10.5