UCLA vs USC prediction and analysis

November 26, 2025
CFB Predictions
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Introduction

The upcoming matchup between the UCLA Bruins and the USC Trojans once again sets the stage for an intense rivalry game loaded with intriguing betting angles. Both teams present contrasting trends and statistical profiles that are critical to consider for handicapping this contest. Here, we break down key factors shaping the game and offer a well-rounded prediction.

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Key Trends and Team Performance

  • USC at Home: The Trojans have been dominant on their home turf against non-AP-ranked teams, having secured nine consecutive wins in such matchups. They also boast a strong success rate covering the spread as favorites when playing in California, doing so in nine of their previous 11 games.
  • UCLA Struggles in November & on the Road: The Bruins have been notably challenged in November games against AP-ranked opponents, losing their last seven such contests. Additionally, UCLA has failed to cover the spread in seven of its last eight games played in California, suggesting issues with consistency in familiar settings.
  • Betting Dynamics in Rivalry: While USC has some struggles covering the spread against non-ranked opponents, failing four times in five attempts, the road team (often UCLA) has covered the spread in seven of the last nine meetings between these rivals, hinting at a competitive betting environment despite USC’s dominance.
  • Defensive and Scoring Trends: Most games between these teams and their in-state opponents recently lean toward lower-scoring affairs. Nine of UCLA’s last ten contests against California teams and six of USC’s last seven November games against non-AP-ranked foes have gone under the total points line.

Statistical Matchups and Player Impact

  • USC’s Offensive Prowess: The Trojans rank in the top 10 nationally in red zone efficiency (71.4%) and yards per game (479.2), suggesting their ability to move the ball and capitalize on scoring opportunities.
  • UCLA’s Offensive Challenges: The Bruins rank near the bottom nationally in first-quarter scoring and average point differential, highlighting slow starts and struggles to impose early game pressure, which could prove critical against a fast-starting USC team.
  • Individual Standouts: UCLA’s Makai Lemon is a major threat, ranking third nationally in receiving yards, offering a deep-play threat that could keep UCLA competitive. On special teams, USC’s Mateen Bhaghani ranks 5th in the Big Ten for field goals made, although this stat is less directly impactful for this matchup.

Prediction Summary

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USC enters this game with considerable home-field advantage, a potent offense, and a track record of beating teams like UCLA decisively. UCLA’s recent struggles in key situational metrics, including November game performance and covering spreads in California, reduce their chances of pulling an upset. Moreover, the history of lower-scoring outcomes between these teams suggests a game that, while competitive, may not turn into a shootout.

Expect USC to leverage their early game efficiency and strong offensive execution to take control. However, given the rivalry nature and UCLA’s ability to cover spreads on the road, the margin of victory may not be as wide as some expect. Betting the under appears prudent given the recent trends toward lower total points.

Final Prediction

USC to win a closely contested game, likely by around 7 points, while the total score stays under the posted line.