UCLA vs Ohio State prediction and analysis

November 10, 2025
CFB Predictions
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Matchup Overview

This Week 12 college football showdown features the UCLA Bruins traveling to face the Ohio State Buckeyes. Both teams present contrasting strengths and weaknesses, and a close examination of their recent performances, key player statistics, and defensive metrics will guide our prediction for this encounter.

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Key Player Insights

  • UCLA Bruins: Quarterback Julian Sayin has been in impressive form, posting over 300 passing yards in three straight games, a streak that ties for the longest in the FBS heading into this matchup. This suggests a potent aerial attack that could stretch Ohio State’s defense.
  • Ohio State Buckeyes: Wide receiver Anthony Woods shines with an 89.5% catch rate, tied for first in the Big Ten among qualified players. His reliable hands could be pivotal in capitalizing on passing opportunities against UCLA’s defense.

Defensive and Team Trends

  • Ohio State’s defense is among the best in the nation, leading FBS teams by allowing just 3.2 points in the first half and 4.0 points in the second half per game. This level of defensive discipline will be a significant hurdle for UCLA’s offense.
  • Meanwhile, UCLA struggles early in games, ranking tied for 127th in average first-quarter point differential (-5.3), often putting them in a deficit from the outset.
  • UCLA’s defense also faces challenges on the ground, surrendering 191.1 rushing yards per game, ranking them near the bottom nationally in this category. Ohio State may exploit this gap to establish control and clock management.

Analytical Perspective

The significant defensive prowess of Ohio State, particularly in limiting opponent scoring across all quarters, could stifle UCLA’s offense despite the Bruins’ strong individual performances. The Bruins’ vulnerability to the run and sluggish start could compound these offensive challenges.

Ohio State’s offense, buoyed by dependable receivers like Anthony Woods, is likely to capitalize on offensive opportunities against a UCLA defense that has shown susceptibility, especially against the rush.

Prediction Summary

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Given Ohio State’s staunch defensive record and balanced offensive weapons, coupled with UCLA’s struggles to jumpstart games and defend the run, the Buckeyes are the favorites to control the pace and secure a comfortable victory in this meeting.

Final Prediction

Ohio State Buckeyes to win by 14 points or more.