Tulsa vs Oklahoma State prediction and analysis

September 18, 2025
CFB Predictions
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Matchup Overview

The Tulsa Golden Hurricane travel to face the Oklahoma State Cowboys in a Big 12 vs. American Athletic Conference non-conference clash on September 19, 2025, at Boone Pickens Stadium. Tulsa enters the game with a 1-2 record, aiming to bounce back and reach .500, while the Cowboys are 1-1 overall and looking to recover from a tough loss.

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Key Factors and Team Trends

  • Historical Edge: Oklahoma State has dominated this matchup historically, with Tulsa dropping each of its last 11 games against Big 12 opponents. Additionally, the Cowboys have been nearly unbeatable at home against non-conference foes, winning 16 of their last 17 such games at Boone Pickens Stadium.
  • Recent Form and Spread Trends: Oklahoma State has been struggling recently, losing 10 of its last 11 games overall and failing to cover the spread in their past seven outings. However, they have shown strength in covering spreads against in-state rivals, having covered in the last three games versus Oklahoma teams. Tulsa, conversely, has struggled on the road against the spread but performed well as a September underdog, covering in eight of their last nine games in that situation.
  • Scoring and Defense Insights: Both teams’ performances by quarter reveal defensive vulnerabilities that could affect the outcome. Oklahoma State ranks poorly in allowing points in the third quarter (136th, 14 PPG), but excels at shutting down opponents in the fourth quarter (tied for 1st, 0 PPG allowed). Tulsa has difficulty scoring in the second quarter (2.0 PPG) and concedes heavily in the second half (15.3 PPG allowed), which may give OSU opportunities late.
  • Players to Watch: Oklahoma State’s Sesi Vailahi leads his team in touchdowns, though with just one this season, indicating limited scoring production. Tulsa’s Elijah Green leads all FBS players with three interceptions, highlighting Tulsa’s defensive strength in turnover creation.
  • Betting Angles: The total points line sits at 54.5 with both teams showing tendencies toward low-scoring affairs, as recent games for both have mostly gone under. Tulsa’s history of keeping games close as road underdogs in September may lend value, especially given Oklahoma State’s struggles covering the spread.

Prediction Summary

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Oklahoma State enters this contest as a clear favorite at home, buoyed by their strong record against non-conference opponents at Boone Pickens Stadium and historical dominance over Tulsa. However, the Cowboys’ recent struggles in covering the spread and overall losses cannot be overlooked. Tulsa’s defensive playmakers, particularly Elijah Green, and their success against the spread as underdogs in September add intrigue to this matchup.

Given Oklahoma State’s strong home-field advantage and Tulsa’s offensive challenges, expect the Cowboys to control the second half and pull away. The game is likely to be tightly contested in the first half, reflecting Tulsa’s trend of winning early halves, but Oklahoma State’s fourth-quarter defensive dominance should secure the victory.

Final Prediction: Oklahoma State wins by 10-14 points, likely covering the -11.5 spread but with the game possibly staying under the 54.5 total due to defensive strengths and offensive limitations on both sides.