St. Francis (PA) vs Buffalo prediction and analysis

September 5, 2025
CFB Predictions
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Game Overview

On Saturday afternoon at UB Stadium, the St. Francis (PA) Red Flash will take on the Buffalo Bulls in what shapes up to be an intriguing early-season college football contest. Both teams enter this matchup coming off opening losses in their 2025 campaigns, but the context and expectations between the two programs could not be more different.

Team Assessments

  • St. Francis (PA) Red Flash: The Red Flash endured a tough 2024 season finishing 4-7 overall with a 2-4 record in the Northeast Conference. Their recent performance has shown offensive struggles, as epitomized in their 29-0 loss to Louisiana-Monroe in Week 1 this year, where they managed just 131 total yards with very limited conversion success on third downs (2-of-12). Their defense also struggled significantly against the ground game, surrendering over 300 rushing yards. Although the team will be motivated to rebound at home, their offensive inconsistency remains a concern.
  • Buffalo Bulls: The Bulls enter Week 2 after a promising 9-4 2024 campaign, including a Mid-American Conference winning record and a Bahamas Bowl triumph over Liberty. They faced a challenging opener against Minnesota, falling 23-10 despite staying competitive for much of the game. Offensive production was subpar with only 151 yards total and a disappointing 1-of-11 on third downs. However, their defense performed relatively well, particularly in red zone defense where Buffalo ranked first nationally last season and continued strong early this year.

Key Factors and Matchup Dynamics

  • Offensive Efficiency: Both teams struggled offensively in their openers, but Buffalo’s defensive strengths and home-field advantage provide them with an edge. St. Francis’ inability to stop the run and generate consistent third-down conversions could hamper their scoring opportunities.
  • Defensive Matchups: Buffalo’s disciplined defense should be able to contain St. Francis’ limited offensive weapons, especially given the Red Flash’s poor passing production early in the year.
  • Motivation and Momentum: Buffalo is likely highly motivated to bounce back after a challenging road game versus a Big Ten opponent, while St. Francis has the uphill battle of shaking off a shutout loss and breaking recent negative form.

Prediction Summary

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Considering Buffalo’s stronger overall program trajectory, defensive strengths, and home advantage, they should emerge with a solid win over St. Francis (PA). While both offenses have shown inefficiencies, the Bulls are more likely to find the end zone and control the tempo of the game.

Final Prediction

Buffalo Bulls to win, expected margin 10-14 points.