Notre Dame vs Pittsburgh prediction and analysis

November 14, 2025
CFB Predictions
...

Notre Dame vs Pittsburgh College Football Prediction and Betting Analysis

Team and Venue Context

This Week 12 matchup pits the storied Notre Dame Fighting Irish against the resilient Pittsburgh Panthers at Acrisure Stadium, where Pittsburgh has established a strong home presence in recent non-conference play. Pittsburgh boasts an impressive record, winning seven of the last eight non-conference games at this venue and covering the spread in the last five such home contests. Conversely, Notre Dame struggles to cover the spread on the road against Atlantic Coast Conference (ACC) foes, failing in four of their last five attempts.

Recommended Sports Betting Sites

100% up to $750
50% up to $200
100% up to $200

November Performance Trends

The month of November tells a tale of two teams. Notre Dame has been dominant in this late-season period, securing 27 wins out of 29 games in November historically and covering the spread in seven of their last eight games as a favorite during this month. However, the Irish’s recent performance against the spread has been shaky, failing in five of their previous six games overall despite a #23 ranking in the AP Poll. On the other hand, Pittsburgh has seen a downturn in November results, losing six of the past seven games during this month, which raises questions about their late-season form.

Offensive and Defensive Matchups

  • Personnel Highlights: Raphael Williams Jr. leads the ACC tied for first in receiving touchdowns (6), showcasing his threat in the passing game for Pittsburgh. Meanwhile, Notre Dame’s defense is formidable against the pass, ranking tied for third in interceptions with 16 this season.
  • Quarterback Play: Pittsburgh’s CJ Carr shines with back-to-back games surpassing a 120.0 passer rating, attesting to his recent proficiency and confidence under center.
  • Scoring Trends: Pittsburgh ranks fifth nationally in average third-quarter point differential (+7.2) and sixth in points per game (39.7), highlighting their ability to score consistently and adjust well after halftime. Notre Dame, meanwhile, stands out defensively in the fourth quarter, allowing only 2.6 points per game to opponents, indicating robust late-game defense that can frustrate high-powered offenses.

Betting and Total Points Considerations

Recent games have shown a tendency towards high-scoring affairs. Each of Pittsburgh’s last eight non-conference home games have gone OVER the total points line. Similarly, Notre Dame has seen 10 of its last 12 November games as a favorite hit the OVER, signaling an expectation for offensive fireworks. Bettors should note the contrasting defensive strengths—Pittsburgh’s prolific offense versus Notre Dame’s stout fourth-quarter defense—making total points a compelling betting angle.

Prediction Summary

Bovada

5.0/5
100% up to $750

The clash features a potent Pitt offense led by an efficient CJ Carr and dynamic receiver Raphael Williams Jr. battling a disciplined Notre Dame squad that thrives in November and excels in closing out games defensively. Pittsburgh’s home-field advantage and third-quarter scoring prowess give them early momentum, but Notre Dame’s historical dominance in late-season games and ability to clamp down in the fourth quarter should keep the Fighting Irish competitive through the final minutes.

Considering Notre Dame’s struggles to cover the spread on the road against ACC teams and Pittsburgh’s recent November difficulties, the game might be tightly contested with momentum swings. In terms of the betting spread and predicted outcomes, Notre Dame’s overall resilience and November success as favorites tilt the scales slightly in their favor, particularly if they can capitalize on defensive takeaways. Expect a potentially high-scoring game with strong defensive stands late.

Final Prediction

Notre Dame to win a close contest, covering a moderate spread, with a likely OVER on total points.