Minnesota vs Ohio State prediction and analysis

October 2, 2025
CFB Predictions
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Matchup Overview

The Minnesota Golden Gophers (3-1) are set to face the undefeated Ohio State Buckeyes (4-0) in an anticipated Big Ten clash on October 4, 2025, at Ohio Stadium. Ohio State enters this game favored by 24 points, with an Over/Under set at 44.5. The Buckeyes have demonstrated dominance this season and have a history of October success at home, making this a compelling contest for college football bettors and fans alike.

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Key Factors and Team Trends

  • Ohio State’s October History at Home: The Buckeyes have a remarkable streak, winning their last 26 October games at Ohio Stadium. However, despite their success, they have failed to cover the spread in three of their last four October games as favorites, indicating that while they win convincingly, the betting line may be ambitious.
  • Minnesota’s Struggles and Strengths: The Golden Gophers have lost eight of their last 10 October games against AP-ranked teams, but intriguingly, Minnesota has covered the spread in each of their last four games against ranked opponents. Moreover, Minnesota has a good history as an underdog in October, winning four of their last six underdog games.
  • Offensive and Defensive Matchups: Ohio State boasts the top red zone defense in FBS, allowing only 25% scoring in such situations, and their defense has been stingy, ranking second for first-half opponent points allowed per game (1.5). Minnesota ranks highly in defense as well, particularly in rushing defense (5th in FBS with 65.5 yards allowed per game) and total yards allowed (9th with 230.0 yards per game), which should temper Ohio State’s high-powered offense somewhat.
  • Quarterback Performance: Minnesota’s QB Julian Sayin is coming off an impressive streak with a passer rating above 110 for three consecutive games, showing he can consistently perform at a high level, which could pose challenges for Ohio State’s defense.
  • Game Tempo and Scoring Trends: Ohio State’s last nine conference games at home have mostly gone under the total point line, suggesting a tendency toward lower-scoring, defensively dominated contests at Ohio Stadium. In contrast, Minnesota’s recent underdog games against top 10 teams often go over, indicating an ability to put points on the board even in difficult matchups.

Analysis

Ohio State remains a powerhouse, especially at home in October, with an unblemished record that underscores their experience and depth. Their elite defense and efficient offense give them the tools to control both sides of the ball. However, Minnesota’s ability to cover spreads against ranked teams and their strong defensive ranks suggest they have the resilience and tactical approach to keep this game competitive.

The game sets up as a classic showdown between Ohio State’s strength and Minnesota’s disciplined defense. With Minnesota’s competent rushing defense limiting big plays on the ground and Julian Sayin’s consistency at quarterback helping to sustain drives, Minnesota could challenge Ohio State more than the spread implies.

That said, Ohio State’s overwhelming home field advantage and prolific scoring efficiency, particularly in the red zone, provide them a clear edge. The key concern for bettors is the large spread of 24 points, which has historically been difficult for Ohio State to consistently cover, especially in recent Octobers.

Prediction Summary

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Expect Ohio State to control this game thanks to their superior talent and home dominance. However, Minnesota should keep the final margin closer than the betting line suggests, with a moderately competitive game unfolding. Given Minnesota’s recent ability to cover as underdogs and Ohio State’s occasional struggles to cover big spreads in October, a bet on Minnesota covering the 24-point line presents value. The under 44.5 total also looks appealing given Ohio State’s recent games at home trending under.

Final Prediction

Ohio State wins by 14 points, with Minnesota covering the spread. Consider Ohio State -14 as a more realistic margin and evaluating the under on total points at 44.5.