Indiana vs Purdue prediction and analysis

November 28, 2025
CFB Predictions
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Team Recap and Context

The stage is set for an intense Week 14 clash as the Indiana Hoosiers visit the Purdue Boilermakers at Ross-Ade Stadium. Indiana enters this game unbeaten and determined to maintain their perfect record, while Purdue is eager to secure a meaningful first Big Ten win and assert their dominance at home against their in-state rival.

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Key Betting and Performance Trends

  • Home advantage and rivalry history: Purdue has a strong track record at home against Indiana teams, winning five of their last six encounters at Ross-Ade Stadium. However, Indiana has struggled on the road in this venue, losing three of their last four games there.
  • Spread behavior: Despite Indiana’s high AP ranking (2nd), they have underperformed against the spread in eight of their last ten games. Conversely, the underdog has often covered the spread at Purdue in recent matchups.
  • Conference game trends: Purdue is on a tough skid with 17 straight losses against conference opponents, highlighting their challenges within the Big Ten.
  • Scoring tendencies: Both teams’ recent performances suggest this game could trend towards a high scoring affair, with many of Indiana’s November road games and Purdue’s recent home underdog contests going over the total points line.

Statistical Insights and Player Impact

  • Indiana’s offense is led by quarterback Fernando Mendoza, who shares the FBS lead with 30 passing touchdowns this season, showcasing his elite playmaking capabilities.
  • On the ground, Purdue relies on Devin Mockobee, a dual-threat back averaging more than 50 rushing yards and 20 receiving yards per game, making him a key offensive weapon.
  • Defensively, Purdue has struggled to contain opponents in the second quarter, ranking near the bottom in points allowed and point differential during that period.

Game Flow and Tactical Considerations

Indiana’s dominance in the early stages of conference games is noteworthy — they have won the first quarter in each of their last 11 such games and the first half in every recent contest. Purdue, while tough at home, has at times struggled to build leads, particularly in the second quarter, which could be a critical phase for Indiana to exploit.

Prediction Summary

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Considering Indiana’s impeccable road form against non-ranked teams, their superior offensive firepower, and Purdue’s defensive vulnerabilities in key quarters, the Hoosiers appear poised to control the game tempo. Although Purdue’s home history against in-state teams and resilience in the first quarter will provide resistance, the overall balance favors Indiana maintaining their unbeaten status.

Prediction: Indiana Hoosiers to win by 10+ points.