Colorado State vs Wyoming prediction and analysis

October 21, 2025
CFB Predictions
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Game Overview

The Mountain West clash between the Colorado State Rams (2-5) and the Wyoming Cowboys (3-4) on October 25, 2025, promises to be a pivotal contest as both teams seek to improve their conference records. Wyoming enters as a 5.5-point favorite at home in Jonah Field at War Memorial Stadium, with an over/under of 46.5 points. This rivalry game will test the offensive and defensive strengths of two teams navigating challenging seasons.

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Key Factors and Recent Trends

  • Wyoming’s Home Advantage: The Cowboys boast a formidable home field edge, having won each of their last nine home games against teams from Colorado, including Colorado State. Additionally, the home team has covered the spread in each of the last six matchups between these teams, emphasizing Wyoming’s dominance on their turf.
  • Colorado State’s Road Struggles: The Rams have struggled as underdogs on the road, losing their last seven such games and failing to cover the spread in their last four appearances at Jonah Field. This raises concerns about their ability to overcome Wyoming’s home field advantage.
  • October Performance Woes for Wyoming: Despite their home success, Wyoming has been inconsistent in October, losing seven of their last eight games in this month, which could be a critical vulnerability.
  • Spread Covering Patterns: Interestingly, Colorado State has been successful as an underdog in recent matches across the board but has faltered at this venue. The underdog has covered six of Colorado State’s last seven games, but Wyoming has struggled to cover as a favorite against Colorado teams.
  • Scoring Trends and Defense: Both teams have shown questionable offensive consistency. Wyoming ranks near the bottom nationally for first-half and second-quarter scoring, which may limit their capacity for a decisive early lead. Colorado State also struggles particularly after halftime, ranking poorly in third-quarter scoring and second-quarter point differential. Historically, most first halves between these sides have favored Wyoming, but both defenses have shown moments of resilience.

Player Highlights

  • Desman Hearns (Wyoming): Leads the Mountain West in forced fumbles with 2, signaling a disruptive defensive presence that could create turnover opportunities.
  • Owen Long (Colorado State): The conference leader in tackles with 76, he will be central to limiting Wyoming’s offensive production and rallying the Rams’ defense.

Scoring and Total Points Outlook

Colorado State’s recent road games have largely gone over the total points line, while Wyoming’s home games tend to go under. This contrast suggests a potentially tighter defensive battle, leaning toward a safer under bet given both teams’ offensive struggles and defensive capabilities.

Prediction Summary

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Considering Wyoming’s strong home-field advantage and historical dominance against Colorado State at War Memorial Stadium, they are favored to extend their winning streak in this rivalry. However, Wyoming’s recent October struggles and subpar scoring in the early quarters suggest the game may be closer than the spread implies. Colorado State’s inability to cover as a road underdog here tempers their upset chances.

Expect a competitive game where Wyoming controls enough possession to maintain a lead, but the Rams keep it within a touchdown. The total points likely stay under the posted 46.5 given both teams’ conservative second-half outputs.

Final Prediction

Wyoming wins 24-17, covering the 5.5-point spread.