A smoker holds a cigarette on May 31, 2011 in San Francisco, California.
CLEVELAND - Smokers are being asked to give up the single largest preventable cause of disease and premature death in America: Tobacco.
It's used by nearly one-fifth of Americans every day.
READ: Success stories by northeast Ohioans who've kicked the habit
Thursday is the Great American Smokeout . The smokeout is sponsored by the American Cancer Society.
It's all about encouraging smokers to quit and educating everyone on the health risks and financial costs.
For example: Every cigarette smoked cuts your life expectancy by five minutes and smoking just twice a day over a year would set you back $200.