Agents were called back to the home Friday morning as part of the investigation into Acevedo's 293-count indictment, filed Thursday.
Acevedo's indictment includes the aggravated murder of Pemberton in 1994 and of an unidentified woman in 1995, the same month that Christina Adkins went missing.
Investigators have searched the house at least once before, soon after his June arrest for a 1993 rape that occurred in the same field in which Pemberton's body was found.
Acevedo's home on Vega Avenue, which today stands vacant, was just a few doors down from Pamela Pemberton's home.
Pemberton was killed and left naked in Tremont, near West 11th Street and Clark Avenue, not long before Christina Adkins, an 18-year-old who was five months pregnant, disappeared from the same area.
He's also been charged with the rape and kidnapping of two girls when they were as young as 8 and 11, and, a few months ago, was charged in a 1993 rape case.
In all, Acevedo faces four counts of aggravated murder, 173 counts of rape, 115 counts of kidnapping and one count of gross sexual imposition; plus two counts of rape and one of kidnapping from the 1993 case.
Acevedo is scheduled to be arraigned in Cuyahoga County Common Pleas Court Monday at 8:30 a.m.