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2008 U-C-F Knights Schedule
| Date | Time (ET) | Opponent | Result | Record |
| 08/30/2008 | 06:00 PM | SC State | W, 17-0 | 1-0-0 |
| 09/06/2008 | 07:00 PM | So Florida | L, 31-24 | 1-1-0 |
| 09/20/2008 | 01:00 PM | at Boston College | L, 34-7 | 1-2-0 |
| 09/27/2008 | 08:00 PM | at Texas-El Paso | L, 58-13 | 1-3-0 |
| 10/04/2008 | 03:30 PM | S-M-U | W, 31-17 | 2-3-0 |
| 10/11/2008 | 03:45 PM | at Miami-Florida | L, 20-14 | 2-4-0 |
| 10/26/2008 | 08:00 PM | at Tulsa | L, 49-19 | 2-5-0 |
| 11/02/2008 | 08:00 PM | East Carolina | L, 13-10 | 2-6-0 |
| 11/08/2008 | 03:30 PM | Southern Miss | L, 17-6 | 2-7-0 |
| 11/15/2008 | 04:30 PM | at Marshall | W, 30-14 | 3-7-0 |
| 11/22/2008 | 02:00 PM | at Memphis | W, 28-21 | 4-7-0 |
| 11/29/2008 | 01:00 PM | U-A-B | L, 15-0 | 4-8-0 |
